89472-50-4Relevant articles and documents
6α-Methylprednisolone derivatives
-
, (2008/06/13)
A 6α-methylprednisolone derivative of the general formula: STR1 wherein R1 is a hydrogen atom or stands for the grouping STR2 where R3 is a straight or once-branched chain C1-4 alkyl group, a phenyl group or a lower alkoxy- or alkylthio-methyl group, and R2 is a straight or once-branched chain C1-4 alkyl group, a phenyl group or a lower alkoxy- or alkylthio-methyl group, with the proviso that when R2 is ethyl group, R1 should not be a hydrogen atom or R3 should not be ethyl group. This compound exhibits a strong local antiinflammatory effect and is, therefore, useful as a harmless external antiinflammatory drug for various dermal disorders and also as an antiallergic drug for treating asthma and the like allergic diseases.