894801-95-7Relevant academic research and scientific papers
Synthesis and antimicrobial activity of novel 1-[3-(1,8-naphthyridin-2-yl)phenyl]-3-arylurea derivatives
Bhasker, G Vijaya,Satyanarayana,Latha,Laxminarayana,Chary, M Thirumala
, p. 771 - 774 (2018/03/13)
2-Aminonicotinaldehyde (1) and 1-(3-nitrophenyl)ethanone (2) react each other in presence of piperidine to form 2-(3-nitrophenyl)-1,8-naphthyridine (3). Compound 3 on reduction with hydrazine hydrate offered 3-(1,8-naphthyridin-2-yl)aniline (4), which on
(4-TERT-BUTYLPIPERAZIN-2-YL)(PIPERAZIN-1-YL)METHANONE-N-CARBOXAMIDE DERIVATIVES
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Page/Page column 16, (2010/06/22)
The present invention relates to compounds of formula (I) The compounds act via antagonism of the CCR2b receptor and may be used to treat inflammatory disease and/or neuropathic pain.
NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE
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Page/Page column 25-26, (2009/10/18)
The present invention relates to a study on the sy nthesis of a novel N-(2-aminophenyl)benzamide derivativ e having an urea structure and represented by the genera l formula (1); and the utilization of a pharmacological effect of the derivative. A compoun
HETEROCYCLIC COMPOUNDS AS CCR2B ANTAGONISTS
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Page/Page column 205, (2008/06/13)
Compounds of formula (I) Q-L-W-C(=X)-Z-P wherein Q is an amine of the formula-N (R1)(R2); L is an alkyl or heterocyclyl-alkyl linker; W is a 6-or 7-membered aliphatic ring comprising ring atoms Y1 and Y2 which are linked to groups L and C(X) respectively and Y1 and Y2 are independently selected from N and C; X is O, N, N-CN or S; Z is NR 3; P is an optionally substituted monocyclic or bicyclic aryl or heteroaryl group; and pharmaceutically acceptable salts or solvates thereof, are useful in the treatment of C-C chemokine mediated conditions.
