894803-67-9 Usage
Uses
Used in Medicinal Chemistry:
2,5-dimethoxy-4-methylthio-phenylethanol is used as an intermediate in the synthesis of pharmaceuticals for its potential to contribute to the development of new drugs. Its unique structure and functional groups may offer novel therapeutic properties in various medicinal applications.
Used in Perfumery:
2,5-dimethoxy-4-methylthio-phenylethanol is used as a fragrance ingredient in the perfumery industry due to its aromatic nature. Its distinct scent profile can be utilized to create unique and complex fragrances for various consumer products.
Used in Flavoring Industry:
In the flavoring industry, 2,5-dimethoxy-4-methylthio-phenylethanol is used as a flavoring agent to impart specific taste profiles to food and beverage products. Its unique flavor characteristics can enhance the sensory experience of various consumables.
Used in Biological Research:
2,5-dimethoxy-4-methylthio-phenylethanol is used in biological research as a compound of interest for its potential pharmacological properties. The presence of the methylthio group may contribute to its biological activity, making it a candidate for further investigation into its effects on various biological systems.
Further research is necessary to fully explore the potential uses and effects of 2,5-dimethoxy-4-methylthio-phenylethanol across different industries and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 894803-67-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,4,8,0 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 894803-67:
(8*8)+(7*9)+(6*4)+(5*8)+(4*0)+(3*3)+(2*6)+(1*7)=219
219 % 10 = 9
So 894803-67-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H16O3S/c1-7(12)8-5-10(14-3)11(15-4)6-9(8)13-2/h5-7,12H,1-4H3
894803-67-9Relevant academic research and scientific papers
Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity
Szczepankiewicz, Bruce G.,Kosogof, Christi,Nelson, Lissa T. J.,Liu, Gang,Liu, Bo,Zhao, Hongyu,Serby, Michael D.,Xin, Zhili,Liu, Mei,Gum, Rebecca J.,Haasch, Deanna L.,Wang, Sanyi,Clampit, Jill E.,Johnson, Eric F.,Lubben, Thomas H.,Stashko, Michael A.,Olejniczak, Edward T.,Sun, Chaohong,Dorwin, Sarah A.,Haskins, Kristi,Abad-Zapatero, Cele,Fry, Elizabeth H.,Hutchins, Charles W.,Sham, Hing L.,Rondinone, Cristina M.,Trevillyan, James M.
, p. 3563 - 3580 (2007/10/03)
The c-Jun N-terminal kinases (JNK-1, -2, and -3) are members of the mitogen activated protein (MAP) kinase family of enzymes. They are activated in response to certain cytokines, as well as by cellular stresses including chemotoxins, peroxides, and irradiation. They have been implicated in the pathology of a variety of different diseases with an inflammatory component including asthma, stroke, Alzheimer's disease, and type 2 diabetes mellitus. In this work, high-throughput screening identified a JNK inhibitor with an excellent kinase selectivity profile. Using X-ray crystallography and biochemical screening to guide our lead optimization, we prepared compounds with inhibitory potencies in the low-double-digit nanomolar range, activity in whole cells, and pharmacokinetics suitable for in vivo use. The new compounds were over 1000-fold selective for JNK-1 and -2 over other MAP kinases including ERK2, p38α, and p38δ and showed little inhibitory activity against a panel of 74 kinases.
