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2,6-Dichloro-4-ethoxypyridine is a chloropyridine-based organic compound with the molecular formula C7H6Cl2NO. It is characterized by the presence of two chlorine atoms and an ethoxy group attached to a pyridine ring, making it a valuable intermediate in various industrial manufacturing processes.

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  • 894804-42-3 Structure
  • Basic information

    1. Product Name: 2,6-Dichloro-4-ethoxypyridine
    2. Synonyms: 2,6-Dichloro-4-ethoxypyridine
    3. CAS NO:894804-42-3
    4. Molecular Formula: C7H7Cl2NO
    5. Molecular Weight: 192.04
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 894804-42-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 2,6-Dichloro-4-ethoxypyridine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2,6-Dichloro-4-ethoxypyridine(894804-42-3)
    11. EPA Substance Registry System: 2,6-Dichloro-4-ethoxypyridine(894804-42-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 894804-42-3(Hazardous Substances Data)

894804-42-3 Usage

Uses

Used in Chemical Industry:
2,6-Dichloro-4-ethoxypyridine is used as an intermediate in the production of several agrochemicals, contributing to the development of effective and efficient products for agricultural applications.
Used in Organic Synthesis:
2,6-Dichloro-4-ethoxypyridine is utilized as a key component in organic synthesis, allowing for the creation of a wide range of chemical compounds with diverse applications across various industries.
Precautions:
Due to the reactivity of 2,6-Dichloro-4-ethoxypyridine, it is essential to exercise caution and follow proper safety protocols while handling 2,6-Dichloro-4-ethoxypyridine in industrial settings to prevent potential hazards.

Check Digit Verification of cas no

The CAS Registry Mumber 894804-42-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,4,8,0 and 4 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 894804-42:
(8*8)+(7*9)+(6*4)+(5*8)+(4*0)+(3*4)+(2*4)+(1*2)=213
213 % 10 = 3
So 894804-42-3 is a valid CAS Registry Number.

894804-42-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,6-Dichloro-4-ethoxypyridine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:894804-42-3 SDS

894804-42-3Downstream Products

894804-42-3Relevant articles and documents

Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity

Szczepankiewicz, Bruce G.,Kosogof, Christi,Nelson, Lissa T. J.,Liu, Gang,Liu, Bo,Zhao, Hongyu,Serby, Michael D.,Xin, Zhili,Liu, Mei,Gum, Rebecca J.,Haasch, Deanna L.,Wang, Sanyi,Clampit, Jill E.,Johnson, Eric F.,Lubben, Thomas H.,Stashko, Michael A.,Olejniczak, Edward T.,Sun, Chaohong,Dorwin, Sarah A.,Haskins, Kristi,Abad-Zapatero, Cele,Fry, Elizabeth H.,Hutchins, Charles W.,Sham, Hing L.,Rondinone, Cristina M.,Trevillyan, James M.

, p. 3563 - 3580 (2006)

The c-Jun N-terminal kinases (JNK-1, -2, and -3) are members of the mitogen activated protein (MAP) kinase family of enzymes. They are activated in response to certain cytokines, as well as by cellular stresses including chemotoxins, peroxides, and irradiation. They have been implicated in the pathology of a variety of different diseases with an inflammatory component including asthma, stroke, Alzheimer's disease, and type 2 diabetes mellitus. In this work, high-throughput screening identified a JNK inhibitor with an excellent kinase selectivity profile. Using X-ray crystallography and biochemical screening to guide our lead optimization, we prepared compounds with inhibitory potencies in the low-double-digit nanomolar range, activity in whole cells, and pharmacokinetics suitable for in vivo use. The new compounds were over 1000-fold selective for JNK-1 and -2 over other MAP kinases including ERK2, p38α, and p38δ and showed little inhibitory activity against a panel of 74 kinases.

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