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Usage

Uses

Used in Pharmaceutical Production:
1,4-DIIODO-2-NITRO-BENZENE is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a key component in the development of new drugs, particularly those targeting specific medical conditions.
Used in Organic Compound Synthesis:
In the field of organic chemistry, 1,4-DIIODO-2-NITRO-BENZENE serves as a precursor for the production of other organic compounds. Its reactivity and functional groups make it a valuable building block for creating a range of specialized organic molecules for various applications.
Used in Chemical Research:
1,4-DIIODO-2-NITRO-BENZENE is also employed in chemical research to study the properties and reactions of nitro compounds. Its use in laboratories helps scientists understand the behavior of similar compounds and develop new methods for their synthesis and application.

InChI:InChI=1/C6H3I2NO2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H

Upstream product

• 20691-72-9 4-iodo-2-nitroaniline 
• 99-09-2 3-nitro-aniline 
• 5307-14-2 2-nitro-1,4-phenylenediamine 
• 88-74-4 2-nitro-aniline 
• 105752-04-3 3-nitro-4-iodoaniline 

Downstream Products

• 113639-27-3 1-nitro-2,5-diethynylbenzene 
• 440369-65-3 thioacetic acid S-{4-[4-(4-acetylsulfanylphenylethynyl)-2-nitrophenylethynyl]phenyl} ester 

Relevant academic research and scientific papers

Regioselective Iodine/Zinc Exchange for the Selective Functionalization of Polyiodinated Arenes and Heterocycles in Toluene

Regioselective I/Zn-exchange reactions were performed on polyiodinated arenes or heterocycles within 20 minutes at 0-25 °C using the bimetallic combination pTol2Zn2LiOR [R = (CH2)2N(Me)(CH2)2NMe2] in toluene. The resulting diaryl- or diheteroarylzincs reacted well with allylic bromides and acyl chlorides to provide functionalized (hetero)- aryl iodides in good yields.

Nucleotides and nucleosides and methods for their use in DNA sequencing

The present invention relates generally to labeled and unlabled cleavable terminating groups and methods for DNA sequencing and other types of DNA analysis. More particularly, the invention relates in part to nucleotides and nucleosides with chemically cleavable, photocleavable, enzymatically cleavable, or non-photocleavable groups and methods for their use in DNA sequencing and its application in biomedical research.

Synthesis of functionalized nitroarylmagnesium halides via an iodine-magnesium exchange

(Chemical Equation Presented) Various nitro-substituted aryl and heteroaryl iodides undergo an iodine-magnesium exchange reaction when treated with PhMgCl leading to nitro-containing magnesium organometallics. These Grignard reagents display an excellent stability at temperatures below -40°C and do not undergo electron-transfer reactions. They react as expected with various electrophiles.

Synthesis of terphenyl oligomers as molecular electronic device candidates

Six functionalized bis(phenylene ethynylene)-p,p-terphenyls (BPETs) have been synthesized as potential molecular electronic devices. The molecules containing mono- and dinitro terphenyl cores, were rationally designed based on the electronic properties recently found in oligo(phenylene ethynylene)s (OPEs). From our understanding of the conductance properties in OPEs, improvement of electronic properties may be possible by using BPETs due to a higher rotational barrier between the central aromatic rings of the compounds prepared here. BPETs cores were functionalized with nitro groups and with different metallic adhesion moieties (alligator clips) to provide new compounds for testing in the nanopore and planar testbed structures.