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1-(o-trifluoromethylphenyl)-3-phenylurea is a chemical compound with the molecular formula C15H11F3N2O. It is a derivative of urea, featuring a phenyl group attached to the nitrogen atom at position 3 and an o-trifluoromethylphenyl group at position 1. 1-(o-trifluoromethylphenyl)-3-phenylurea is known for its potential applications in the synthesis of agrochemicals and pharmaceuticals, particularly as a precursor in the production of herbicides and other bioactive molecules. Its structure provides a unique combination of electronic and steric properties, which can influence its reactivity and interaction with target molecules. The presence of the trifluoromethyl group can enhance the lipophilicity and metabolic stability of the compound, which are important factors in drug design.

895-40-9

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895-40-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 895-40-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,9 and 5 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 895-40:
(5*8)+(4*9)+(3*5)+(2*4)+(1*0)=99
99 % 10 = 9
So 895-40-9 is a valid CAS Registry Number.

895-40-9Downstream Products

895-40-9Relevant academic research and scientific papers

Ortho-substituent effects on diphenylurea packing motifs

Solomos, Marina A.,Watts, Taylor A.,Swift, Jennifer A.

, p. 5065 - 5072 (2017)

Hydrogen bonding between urea groups is a widely used motif in crystal engineering and supramolecular chemistry studies. In an effort to discern how the steric and electronic properties of substituents affect the molecular conformation and crystal packing

Synthesis and structure activity relationships in diphenylureas against Culex quinouefasciatus

Minatchy, S.,Mathew, Nisha

, p. 1066 - 1068 (2007/10/03)

Substituted diphenylureas 1-23 have been synthesised from isocyanates generated from azides of benzoic acid and 4-chlorobenzoic acid with aniline, and 4-chloro-, 2-trifluoromethyl-, 3-trifluoromethyl, 4-phenoxy-, 2,4-dichloro-, 2,5-dichloro-, 3,4-dichloro-, 3-chloro-4-methoxy-, 3-chloro-2-methyl-, 3-chloro-4-methyl- and 4-nitro-anilines. All the compounds have been tested for insect growth regulating (IGR) activity against early third instar larvae of Culex quinquefasciatus, the human filariasis vector. Compounds 15 and 19 exhibit 100 percent emergence inhibition at 1 ppm concentration against Cx quinquefasciatus larvae. These compounds may play a useful role in mosquito control by maintaining the vector populations at a minimum level.

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