895-45-4 Usage
General Description
2-[[4-(trifluoromethyl)phenyl]thio]benzoic acid is a chemical compound with the molecular formula C14H9F3O2S. It is a white to off-white powder that is sparingly soluble in water. 2-[[4-(TRIFLUOROMETHYL)PHENYL]THIO] BENZOIC ACID is often used as a building block for the synthesis of various pharmaceutical compounds and agrochemicals. It is also used as an intermediate in the production of dyes, pigments, and other organic compounds. Additionally, it has anti-inflammatory properties and is used in the development of drugs for conditions such as rheumatoid arthritis and osteoarthritis. Furthermore, it is a potential target for drug discovery due to its role in various biological processes. However, it is important to handle and use this compound with caution, as it may be harmful if ingested or inhaled and can cause irritation to the skin and eyes.
Check Digit Verification of cas no
The CAS Registry Mumber 895-45-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 8,9 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 895-45:
(5*8)+(4*9)+(3*5)+(2*4)+(1*5)=104
104 % 10 = 4
So 895-45-4 is a valid CAS Registry Number.
InChI:InChI=1/C14H9F3O2S/c15-14(16,17)9-5-7-10(8-6-9)20-12-4-2-1-3-11(12)13(18)19/h1-8H,(H,18,19)
895-45-4Relevant articles and documents
Preparation method of 2-(p-trifluoromethyl thiophenyl)benzoate
-
Paragraph 0015; 0016; 0017; 0018; 0019; 0020; 0021, (2017/09/29)
The invention provides a preparation method of 2-(p-trifluoromethyl thiophenyl)benzoate. The 2-(p-trifluoromethyl thiophenyl)benzoate is obtained by reacting thiosalicylic acid serving as a starting raw material with p-trifluoromethyl chlorobenzene. Compared with the prior art, the preparation method mainly has the advantages: (1) an organic solvent obtained by post-treatment can be recycled, so that the emission of waste water, waste gas and waste solid is reduced, and the production cost is lowered; (2) a water phase obtained by post-treatment can also be recycled, and sodium chloride in the water phase can be recycled after repeated use, so that wastewater is recycled, water resources are saved, and the atom economy is increased; (3) the 2-(p-trifluoromethyl thiophenyl)benzoate content of a synthesized flupentixol intermediate can be 90 percent or more, the highest content can be up to 93 percent, and the content of the 2-(p-trifluoromethyl thiophenyl)benzoate obtained by an original process method is only about 85 percent. The whole process meets the technical requirements of environment-friendly synthesis and clean production, and is suitable for large-scale industrial production.
