895138-20-2Relevant academic research and scientific papers
A unified approach to the synthesis of both enantiomers of anatoxin-a and homoanatoxin-a cyanotoxins
Addante-Moya, Luis G.,Agulló, Consuelo,Qui?ones-Reyes, Guillermo,Mercader, Josep V.,Abad-Fuentes, Antonio,Abad-Somovilla, Antonio
, p. 5022 - 5031 (2018)
Anatoxin-a and homoanatoxin-a are highly neurotoxic compounds produced by cyanobacteria, principally during surface water-blooms (SWBs). Owing to their powerful biological activity and unique structural characteristics, these natural alkaloids have been t
Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes
Carroll, F. Ivy,Hu, Xingding,Navarro, Hernán A.,Deschamps, Jeffrey,Abdrakhmanova, Galya R.,Damaj, M. Imad,Martin, Billy R.
, p. 3244 - 3250 (2007/10/03)
(±)-Pyrido[3,4-b]homotropane [(±)-1] is a conformationally rigid analogue of nicotine (2) or nornicotine (3) that showed high affinity for nicotinic acetylcholine receptors. Even though the synthesis and potent activity of this highly interesting compound
