895147-26-9

Upstream product

• 895147-32-7 N-(5-{2-[(2,3-difluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-3-yl)-2,2,2-trifluoroacetamide 

Downstream Products

• 895147-55-4 N-(2,3-difluorophenyl)-2-{3-[(7-ethoxy-5-methoxyquinazolin-4-yl)amino]-1H-pyrazol-5-yl}acetamide 

Relevant academic research and scientific papers

Novel quinazoline-containing compound, and intermediate and application thereof

The present invention discloses a quinazoline-containing compound having the formula (IA), (IB) or (IC), or a pharmaceutically acceptable salt or a prodrug molecule thereof. The compound is suitable for use as an Aurora kinase inhibitor and is thus suitable for the treatment of Aurora-mediated diseases characterized by excessive or abnormal cell proliferation, for example, cancer.

PYRAZOLYLAMINO SUBSTITUTED QUINAZOLES FOR THE TREATMENT OF CANCER

The invention provided a compound of formula: (I) for use in the treatment of disease, in particular proliferative diseases such as cancer and for use in the preparation of medicaments for use in the treatment of proliferative diseases; the invention also