895240-77-4 Usage
General Description
4-Ethyl-3-(3-methoxypropoxyl)benzoic acid, also known as Eptifibatide, is a synthetic peptide that acts as an antagonist of platelet aggregation. It is used as an antiplatelet medication and is commonly prescribed to patients who have undergone certain cardiovascular procedures, such as angioplasty. Eptifibatide works by blocking the glycoprotein IIb/IIIa receptor on the surface of platelets, thereby preventing the formation of blood clots. This helps to reduce the risk of complications such as heart attacks and strokes. Eptifibatide is administered intravenously and is typically given in a hospital setting under the supervision of healthcare professionals. Side effects may include bleeding, bruising, and dizziness, and it is important for patients to be closely monitored while receiving this medication.
Check Digit Verification of cas no
The CAS Registry Mumber 895240-77-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,5,2,4 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 895240-77:
(8*8)+(7*9)+(6*5)+(5*2)+(4*4)+(3*0)+(2*7)+(1*7)=204
204 % 10 = 4
So 895240-77-4 is a valid CAS Registry Number.
895240-77-4Relevant articles and documents
The P1 N-isopropyl motif bearing hydroxyethylene dipeptide isostere analogues of aliskiren are in vitro potent inhibitors of the human aspartyl protease renin
Yamaguchi, Yasuchika,Menear, Keith,Cohen, Nissim-Claude,Mah, Robert,Cumin, Frédéric,Schnell, Christian,Wood, Jeanette M.,Maibaum, Jürgen
scheme or table, p. 4863 - 4867 (2010/05/18)
Novel nonpeptide small molecule renin inhibitors bearing an N-isopropyl P1 motif were designed based on initial lead structures 1 and aliskiren (2). (P3-P1)-Benzamide derivatives such as 9a and 34, as well as the corresponding P1 basic tertiary amine derivatives 10 and 35 were found to display low nanomolar inhibition against human renin in vitro.