89530-36-9Relevant academic research and scientific papers
Alkylmetal Asymmetric Reduction. 14. Enantioselective Reduction of Ketones by Chiral (2-Methylbutyl)aluminum Derivatives
Giacomelli, Giampaolo,Lardicci, Luciano,Palla, Fabio,Caporusso, Anna Maria
, p. 1725 - 1728 (1984)
The reaction of trisaluminum with some α-alkynyl ketones has been studied: the organoaluminum derivative rapidly reduces the ketones to afford optically active α-alkynyl carbinols, which can be recovered after hydrolytic workup.The sterochemical results obtained are discussed on the basis of previous reports on enantioselective reductions of ketones by an alkylaluminum dichloride derived from β-pinene.In this context, an investigation on the reaction between a series of ketones and β-branched alkylaluminum chlorides is also reported.
