89544-65-0Relevant academic research and scientific papers
Antifungal amide and urea derivatives of (3-amino-2-aryl-2-hydroxyprop-1-yl)-1H-1,2,4-triazoles
-
, (2008/06/13)
Compounds of the general formula STR1 or a pharmaceutically acceptable acid addition salt thereof, wherein R is naphthyl, biphenylyl, phenyl or substituted phenyl; and R1 is STR2 where X is O or S, R2 is H, or C1 -C4 alkyl and R3 is H, C1 -C4 alkyl, C3 -C6 cycloalkyl, optionally mono- or disubstituted phenyl, benzyl or Het and Het is pyridyl, pyrimidinyl or pyrazinyl; said substituents being halo, CF3, C1 -C4 alkyl, C1 -C4 alkoxy or hydroxy, or R2 and R3 taken together complete a 1-pyrrolidinyl or piperidino ring; methods for their use in combatting fungal infections in plants and animals, including humans; pharmaceutical and agricultural compositions containing them and intermediates useful in their preparation.
