895532-65-7

Upstream product

• 895532-64-6 (S)-1-((4-bromo-2-methylpent-4-enyloxy)methyl)-4-methoxybenzene 
• 895532-63-5 (3R,4S)-3-(tert-butyldimethylsilyloxy)-4-(2-(methoxymethoxy)ethyl)-2,2-dimethylcyclobutanone 
• 895532-62-4 (1R,3R,4R)-3-(tert-butyldimethylsilyloxy)-4-[2-(methoxymethoxy)ethyl]-2,2-dimethylcyclobutanol 
• 895532-57-7 (1R,3R,4R)-1-(tert-butyldimethylsilyloxy)-3-benzyloxy-2,2-dimethyl-4-(2-methoxymethoxyethyl)cyclobutane 
• 895532-55-5 (1R,3R,4R)-1-(tert-butyldimethylsilyloxy)-3-benzyloxy-2,2-dimethyl-4-vinylcyclobutane 
• 104410-48-2 (2S)-4-bromo-2-methyl-4-penten-2-ol 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 895532-54-4 (1R,3R,4S)-3-benzyloxy-2,2-dimethyl-4-vinylcyclobutanol 

Downstream Products

• 952092-41-0 (1R,3R,4S)-3-(tert-butyldimethylsilyloxy)-1-((S)-5-(4-methoxybenzyloxy)-4-pent-1-en-2-yl)-4-(2-hydroxyethyl)-2,2-dimethylcyclobutanol 
• 952092-42-1 (1R,5S,6R)-6-(tert-butyldimethylsilyloxy)-1-((S)-5-(4-methoxybenzyloxy)-4-pent-1-en-2-yl)-7,7-dimethyl-2-oxabicyclo[3.2.0]heptan-3-one 
• 952092-43-2 (1R,5S,6R)-6-hydroxy-1-((S)-5-(4-methoxybenzyloxy)-4-pent-1-en-2-yl)-7,7-dimethyl-2-oxabicyclo[3.2.0]heptan-3-one 
• 952092-44-3 O-(1R,5S,6R)-1-((S)-5-(4-methoxybenzyloxy)-4-pent-1-en-2-yl)-7,7-dimethyl-3-oxo-2-oxabicyclo[3.2.0]heptan-6-yl O-p-tolyl carbonothioate 
• 952092-45-4 (1S,5R)-1-((S)-5-(4-methoxybenzyloxy)-4-pent-1-en-2-yl)-7,7-dimethyl-2-oxabicyclo[3.2.0]heptan-3-one 

Relevant academic research and scientific papers

Pestalotiopsin A. Side chain installation and exhaustive probing of olefin metathesis as a possible tool for elaborating the cyclononene ring

(Chemical Equation Presented) A program directed toward an asymmetric synthesis of pestalotiopsin A is described. The routing begins with the dextrorotatory cyclobutanol 37, which is combined with the enantiomerically defined building blocks ent-15 and 16

In pursuit of pestalotiopsin A via zirconocene-mediated ring contraction

An asymmetric route from the epimeric β-hydroxy esters 4 and 5 to the densely functionalized (+)-10 and (-)-10, respectively, is described. Either cyclobutanol can be made available as the predominant product. The levorotatory antipode has been transforme