895569-32-1

Basic information

• Product Name: Benzoic acid, 3-(7-hydroxy-1-oxo-2(1H)-isoquinolinyl)-4-methyl-
• CAS NO: 895569-32-1
• Molecular Formula: C17H13NO4
• Molecular Weight: 295.295
• Mol File: 895569-32-1.mol

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3-(7-hydroxy-1-oxo-2(1H)-isoquinolinyl)-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-(7-hydroxy-1-oxo-2(1H)-isoquinolinyl)-4-methyl-(895569-32-1)
• EPA Substance Registry System: Benzoic acid, 3-(7-hydroxy-1-oxo-2(1H)-isoquinolinyl)-4-methyl-(895569-32-1)

Safety Data

• Hazardous Substances Data: 895569-32-1(Hazardous Substances Data)

Upstream product

• 10397-30-5 4-methyl-3-nitrobenzoyl chloride 
• 52962-25-1 2-(carboxymethyl)-5-methoxybenzoic acid 
• 895569-28-5 N-cyclopropyl-3-(7-methoxy-1,3-dioxo-3,4-dihydro-1H-isoquinolin-2-yl)-4-methylbenzamide 
• 303133-89-3 N-cyclopropyl-4-methyl-3-nitrobenzamide 
• 623155-19-1 3-amino-N-cyclopropyl-4-methylbenzamide 
• 4702-29-8 7-methoxy-1H-isochromene-1,3(4H)-dione 
• 895568-26-0 N-cyclopropyl-3-(7-hydroxy-1-oxo-1H-isoquinolin-2-yl)-4-methylbenzamide 

Downstream Products

• 895569-44-5 3-[7-(2-chloroethoxy)-1-oxo-1H-isoquinolin-2-yl]-4-methylbenzoic acid 
• 895569-41-2 4-methyl-3-[7-(2-morpholin-4-ylethoxy)-1-oxo-1H-isoquinolin-2-yl]benzoic acid 
• 895569-42-3 4-methyl-3-[7-(2-piperidin-1-ylethoxy)-1-oxo-1H-isoquinolin-2-yl]benzoic acid 
• 1000016-82-9 2-(5-amino-2-methylphenyl)-7-(2-pyrrolidin-1-ylethoxy)isoquinolin-1(2H)-one 
• 1000016-80-7 4-methyl-3-[1-oxo-7-(2-pyrrolidin-1-ylethoxy)isoquinolin-2(1H)-yl]benzoic acid 
• 895569-31-0 3-[7-[2-(dimethylamino)ethoxy]-1-oxo-1H-isoquinolin-2-yl]-4-methylbenzoic acid 
• 1000016-79-4 2-pyrrolidin-1-ylethyl 4-methyl-3-[1-oxo-7-(2-pyrrolidin-1-ylethoxy)isoquinolin-2(1H)-yl]benzoate 

Relevant articles and documents

ISOQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF CYTOKINE MEDIATED DISEASES

The invention concerns a compound of formula (I) or pharmaceutically-acceptable salts thereof wherein R1, R2, R3, R4, R5 and m are as defined in the specification, processes for their preparation, pha

AMIDE DERIVATIVES

The invention concerns a compound of the Formula I (A chemical formula should be inserted here - please see paper copy enclosed herewith) wherein m is 0-2 and each R1 is a group such as hydroxy, halogeno, trifluoromethyl heterocyclyl and heterocyclyloxy; R2 is halogeno, trifluoromethyl or (1-6C)alkyl; R3 is hydrogen, halogeno or (1-6C)alkyl; and R4 is (3-6C)cycloalkyl;or pharmaceutically-acceptable salts thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical condions mediated by cytokines.