895581-52-9

Upstream product

• 15788-16-6 1H-benzimidazole-6-carboxylic acid 
• 26663-77-4 methyl 1H-benzo[d]imidazole-6-carboxylate 
• 895581-42-7 methyl 5-nitro-1H-benzimidazole-6-carboxylate 
• 100-44-7 benzyl chloride 
• 895581-50-7 methyl 1-benzyl-5-nitro-1H-benzimidazole-6-carboxylate 

Downstream Products

• 895581-56-3 methyl 5-amino-1-benzyl-4-[2-(4-methoxyphenyl)ethynyl]-1H-benzimidazole-6-carboxylate 
• 895581-55-2 methyl 5-amino-1-benzyl-4-[2-(4-methylphenyl)ethynyl]-1H-benzimidazole-6-carboxylate 
• 895581-54-1 methyl 5-amino-1-benzyl-4-(2-phenylethynyl)-1H-benzimidazole-6-carboxylate 
• 895581-59-6 methyl 5-amino-4-[2-(4-methoxyphenyl)ethyl]-1H-benzimidazole-6-carboxylate 
• 895581-58-5 methyl 5-amino-4-[2-(4-methylphenyl)ethyl]-1H-benzimidazole-6-carboxylate 
• 895581-46-1 methyl 5-amino-4-phenyl-1H-benzimidazole-6-carboxylate 
• 895581-43-8 methyl 5-amino-1-benzyl-4-iodo-1H-benzimidazole-6-carboxylate 

Relevant academic research and scientific papers

Synthesis, biological evaluation, and crystallographic studies of extended guanine-based (lin-benzoguanine) inhibitors for tRNA-guanine transglycosylase (TGT)

This paper describes the rational design, synthesis, and biological evaluation of a new generation of inhibitors of the bacterial enzyme tRNA-guanine transglycosylase (TGT), which has been identified as a new target in the fight against bacillary dysenter