895581-57-4Relevant articles and documents
Synthesis, biological evaluation, and crystallographic studies of extended guanine-based (lin-benzoguanine) inhibitors for tRNA-guanine transglycosylase (TGT)
Meyer, Emmanuel A.,Donati, Nicola,Guillot, Marine,Schweizer, W. Bernd,Diederich, Francois,Stengl, Bernhard,Brenk, Ruth,Reuter, Klaus,Klebe, Gerhard
, p. 573 - 581 (2006)
This paper describes the rational design, synthesis, and biological evaluation of a new generation of inhibitors of the bacterial enzyme tRNA-guanine transglycosylase (TGT), which has been identified as a new target in the fight against bacillary dysenter