895588-70-2 Usage
Uses
Used in Organic Synthesis:
O-(Benzyloxymethyl)hydroxylamine is employed as a reagent in various organic reactions, facilitating the formation of oximes from carbonyl compounds. Its unique structure allows it to act as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, contributing to the development of new molecules with potential therapeutic and agricultural applications.
Used in Heterocyclic Compound Preparation:
As a versatile building block, O-(Benzyloxymethyl)hydroxylamine is instrumental in the preparation of heterocyclic compounds. These compounds are integral to the creation of complex organic molecules and have broad applications across different chemical and pharmaceutical industries.
Used in Development of Synthetic Methodologies:
O-(Benzyloxymethyl)hydroxylamine also serves as a useful tool in the development of new synthetic methodologies. Its properties and reactivity enable researchers to explore innovative approaches to organic synthesis, potentially leading to more efficient and effective synthetic pathways for the production of various organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 895588-70-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,5,5,8 and 8 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 895588-70:
(8*8)+(7*9)+(6*5)+(5*5)+(4*8)+(3*8)+(2*7)+(1*0)=252
252 % 10 = 2
So 895588-70-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO2/c9-11-7-10-6-8-4-2-1-3-5-8/h1-5H,6-7,9H2
895588-70-2Relevant academic research and scientific papers
Catalytic asymmetric aza-Michael addition of fumaric monoacids with multifunctional thiourea/boronic acids
Michigami, Kenichi,Murakami, Hiroki,Nakamura, Takeru,Hayama, Noboru,Takemoto, Yoshiji
, p. 2331 - 2335 (2019/03/06)
The first chemical enantioselective synthesis of N-hydroxyaspartic acid derivatives using chiral multifunctional thiourea/boronic acid organocatalysts was developed. A series of fumaric monoacids underwent an intermolecular asymmetric aza-Michael addition of O-alkyl hydroxylamines in excellent regioselectivity. The addition of another carboxylic acid raised the enantiomeric enrichment up to 97% ee. O-Deprotection of the aza-Michael adduct provided an aspartate-derived hydroxylamine fragment applicable for KAHA (α-keto acid-hydroxylamine) ligation.
