89570-84-3

Basic information

• Product Name: 2-HYDRAZINO-4-(TRIFLUOROMETHYL)PYRIDINE
• Synonyms: 2-HYDRAZINO-4-(TRIFLUOROMETHYL)PYRIDINE;2-Hydrazino-4-(trifluoromethyl)pyridine 97%;2-Hydrazino-4-(trifluoromethyl)pyridine97%;(4-TRIFLUOROMETHYL-PYRIDIN-2-YL)-HYDRAZINE;2-Hydrazinyl-4-(trifluoroMethyl)pyridine
• CAS NO: 89570-84-3
• Molecular Formula: C₆H₆F₃N₃
• Molecular Weight: 177.13
• Product Categories: Pyridines
• Mol File: 89570-84-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 183℃
• Flash Point: 64℃
• Appearance: /
• Density: 1.46
• Vapor Pressure: 0.00644mmHg at 25°C
• Refractive Index: 1.528
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 2-HYDRAZINO-4-(TRIFLUOROMETHYL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-HYDRAZINO-4-(TRIFLUOROMETHYL)PYRIDINE(89570-84-3)
• EPA Substance Registry System: 2-HYDRAZINO-4-(TRIFLUOROMETHYL)PYRIDINE(89570-84-3)

Safety Data

• Hazard Codes: T
• Hazardous Substances Data: 89570-84-3(Hazardous Substances Data)

Usage

General Description

2-Hydrazino-4-(trifluoromethyl)pyridine is a chemical compound with the formula C6H5F3N4. It is a heterocyclic aromatic compound that contains a pyridine ring with a hydrazino and trifluoromethyl group attached to it. 2-Hydrazino-4-(trifluoromethyl)pyridine is used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has also been studied for its potential applications in organic electronics and materials science. Additionally, 2-Hydrazino-4-(trifluoromethyl)pyridine has shown potential as an inhibitor of DNA gyrase, a bacterial enzyme that plays a crucial role in DNA replication and transcription. Therefore, this compound has potential applications in the development of novel antibacterial agents.

InChI:InChI=1/C6H6F3N3/c7-6(8,9)4-1-2-11-5(3-4)12-10/h1-3H,10H2,(H,11,12)

Upstream product

• 143812-76-4 8-Trifluoromethyl-tetrazolo[1,5-a]pyridine 
• 81565-18-6 2-chloro-4-trifluoromethyl pyridine 

Downstream Products

• 1613150-00-7 7-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one 

Relevant articles and documents

Metal free [4+1] and [5+1] annulation reactions to prepare heterocycles using DMF and its derivatives as one-carbon source

1,2,4-Triazolo[3,4-a]pyridines and related heterocycles and substituted triazines were commonly discovered scaffolds in a variety of pharmaceutical and agrochemical agents. Herein, we report a highly efficient and practical method using DMF and its derivative for the [4+1] and [5+1] annulation reactions to prepare these heterocycles. This metal free reaction takes advantages of shelf stable DMF as solvent and carbon donor, imidazole chloride as a catalyst, the mild reaction condition tolerates a broad substrate range and substitutes. The prepared 3-unsubstituted 1,2,4-triazolo[3,4-a]pyridine and derivatives allow further introduction of a variety of functional group1 at 3-position.

SUBSTITUTED DIHYDROPYRAZOLONES FOR TREATING CARDIOVASCULAR AND HEMATOLOGICAL DISEASES

The invention relates to dihydropyrazolon-derivatives of formula (I), to methods for their production, to their use for treating and/or for preventing diseases and their use for producing medicaments for treating and/or for preventing diseases, in particular cardiovascular and haematological diseases, kidney diseases and for promoting the healing of wounds.

Trifluoromethyl-substituted Dehydrodiazepines and Cyanopyrroles from Azido-/Tetrazolo-pyridines

1,2-Didehydro-1,3-diazepines 4D, 5D, 4,6D and 5,6D are identified as unique products of both photolysis and thermolysis of azido-/tetrazolo-pyridines; the ultimate thermolysis products are trifluoromethylpyrrolecarbonitriles (7-9, 11-13 and 16-18).