89581-48-6

Basic information

• Product Name: Phenol, 4-bromo-2-mercapto-
• CAS NO: 89581-48-6
• Molecular Formula: C6H5BrOS
• Molecular Weight: 205.075
• Mol File: 89581-48-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phenol, 4-bromo-2-mercapto-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-bromo-2-mercapto-(89581-48-6)
• EPA Substance Registry System: Phenol, 4-bromo-2-mercapto-(89581-48-6)

Safety Data

• Hazardous Substances Data: 89581-48-6(Hazardous Substances Data)

Upstream product

• 40925-68-6 2-amino-4-bromo-phenol 
• 7693-52-9 4-bromo-2-nitrophenol 
• 126190-17-8 Dithiocarbonic acid S-(5-bromo-2-hydroxy-phenyl) ester O-ethyl ester 

Downstream Products

• 1381775-54-7 2-((E)-2-(benzo[d][1,3]dioxol-5-yl)vinylthio)-4-bromophenol 
• 126190-01-0 S-(5-Bromo-2-hydroxyphenyl)mercapturic acid 

Relevant articles and documents

Synthesis of Mercapturic Acid Derivatives of Putative Toxic Metabolites of Bromobenzene

The synthesis and characterization of nine isomerically defined S-arylmercapturic acids of interest in connection with the metabolism of the model hepatotoxin bromobenzene is described.Included are three S-(bromophenyl)-, two S-(bromohydroxyphenyl)-, and three S-(bromodihydroxyphenyl)mercapturic acids of defined substitution pattern.In addition, several related compounds with two or no bromine atoms are described.These syntheses depend on two basic methods, 1,4-addition of various arene thiols to acetamidoacrylic acid or the 1,4-addition of N-acetyl-L-cysteine to various benzoquinone derivatives.In addition, we describe a method for efficient conversion of the mercapturic acids to thioanisole derivatives, regioisomers of which can be separed and detected at low levels by capillary gas-liquid chromatography.