896103-70-1 Usage
Uses
Used in Organic Synthesis:
8-Boc-2-hydroxy-1-oxa-8-azaspiro[4.5]decane is used as a building block in organic synthesis for the creation of diverse organic molecules. Its spirocyclic structure and functional groups make it a valuable intermediate for the synthesis of complex organic compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 8-Boc-2-hydroxy-1-oxa-8-azaspiro[4.5]decane is employed as a key intermediate for the synthesis of pharmaceuticals and bioactive compounds. The presence of hydroxyl and amine groups in the compound allows for potential interactions with biological systems, making it a promising candidate for drug development and research.
Used in Drug Development:
8-Boc-2-hydroxy-1-oxa-8-azaspiro[4.5]decane is utilized in drug development as a versatile intermediate for the synthesis of new drugs and therapeutic agents. The selective removal of the Boc protective group under mild conditions enables the exposure of the free amine and hydroxyl functionalities, which can be further modified or functionalized to create bioactive molecules with potential therapeutic applications.
Used in Research:
In research settings, 8-Boc-2-hydroxy-1-oxa-8-azaspiro[4.5]decane serves as a valuable tool for studying the interactions between organic molecules and biological systems. Its unique structure and functional groups allow researchers to explore its potential applications in various fields, such as drug discovery, chemical biology, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 896103-70-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,6,1,0 and 3 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 896103-70:
(8*8)+(7*9)+(6*6)+(5*1)+(4*0)+(3*3)+(2*7)+(1*0)=191
191 % 10 = 1
So 896103-70-1 is a valid CAS Registry Number.
896103-70-1Relevant articles and documents
SPIROCYCLIC COMPOUNDS
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Page/Page column 70-71, (2012/02/02)
Described herein are compounds of formula (I) (Formula (I)). The compounds of formula (I) act as DGAT1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for hyperlipidemia, diabetes mellitus and obesity.
Synthesis of oxaspiropiperidines as a strategy for lowering logD
Cernak, Timothy,Dykstra, Kevin,Levorse, Dorothy,Verras, Andreas,Balkovec, James,Nargund, Ravi,DeVita, Robert
scheme or table, p. 6457 - 6459 (2011/12/22)
The syntheses of four new spiropiperidines designed as polar analogs of methyl 2-(3-azaspiro[5.5]undec-an-9-yl)acetate are described.
G-PROTEIN COUPLED RECEPTOR AGONISTS
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Page/Page column 50-51, (2008/06/13)
Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.
GPCR AGONISTS
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Page/Page column 22, (2010/11/25)
Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.
G-PROTEIN COUPLED RECEPTOR (GPR116) AGONISTS AND USE THEREOF FOR TREATING OBESITY AND DIABETES
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Page/Page column 19, (2008/06/13)
Compounds of formula (I), or pharmaceutically acceptable salts thereof, are agonists of GPR116 and are useful for the treatment of obesity, and for the treatment of diabetes.
4(SPIROPIPERIDINYL)METHYL SUBSTITUTED PYRROLIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
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Page 32, (2010/02/07)
3-Substituted pyrrolidines having a spiropiperidinylmethyl substituent on the 4-position of the ring are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-3 and/or CCR-5.
