896116-37-3

Upstream product

• 536-74-3 phenylacetylene 
• 896114-90-2 5-nitro-3-(phenylethynyl)pyridin-2-amine 
• 15862-31-4 3-bromo-5-nitro-pyridin-2-ylamine 
• 896114-91-3 5-nitro-2-phenyl-1H-pyrrolo[2,3-b]pyridine 
• 1616388-01-2 tert-butyl (2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)carbamate 
• 98-80-6 phenylboronic acid 
• 1616388-00-1 tert-butyl (2-iodo-1H-pyrrolo[2,3-b]pyridin-5-yl)carbamate 
• 1616387-99-5 tert-butyl (2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)carbamate 
• 1001070-33-2 1-(benzenesulfonyl)-5-bromo-1H-pyrrolo[2,3-b]pyridine 
• 183208-35-7 5-bromo-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 1616385-51-3 3,4-dimethyl-N-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazole-5-carboxamide 
• 1616385-74-0 C₁₉H₁₄F₃N₅O 
• 1616385-79-5 ethyl 3-[(2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)carbamoylamino]propanoate 
• 1616385-53-5 N-(2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazole-4-sulfonamide 
• 1027784-90-2 N-cyclopropyl-4-fluoro-3-((2-phenyl-1H-pyrrolo[2,3-b]pyridin-5-ylamino)methyl)benzamide 

Relevant academic research and scientific papers

SYNTHESIS OF HETEROCYCLIC COMPOUNDS

Provided herein are intermediates and processes useful for facile synthesis of compounds of Formula 2: wherein R1 is C(O)R2; R2 is alkyl optionally substituted with 1-5 halogens; G is phenyl or a 5-6 membered heteroaryl op

COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR

Compounds active on c-kit protein kinases or mutant c-kit protein kinases having any mutations are described, as well as methods of making and using such compounds to treat diseases and conditions associated with aberrant activity of the c-kit protein kinases and/or mutant c-kit protein kinases.

NOVEL KINASE INHIBITORS

The present invention provides compounds of Formula (I), and pharmaceutically acceptable salts thereof. The Formula (I) compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1 and IGFR-1, thereby making them usefu

Benzamide Derivatives, Their Manufacture and Use as Pharmaceutical Agents

Objects of the present invention are the compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.

Heterocyclic Carbamate Derivatives, Their Manufacture And Use As Pharmaceutical Agents

Objects of the present invention are the compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.