896160-35-3

Usage

Uses

Used in Pharmaceutical Industry:
2-chloro-5-(3-(trifluoromethyl)benzamido)benzoic acid is used as a chemical intermediate for the synthesis of a variety of pharmaceutical drugs. Its aromatic amido structure and the presence of different functional groups make it a valuable building block in the development of potent medicinal compounds.
Used in Drug Development:
2-chloro-5-(3-(trifluoromethyl)benzamido)benzoic acid is used as a precursor in the creation of new drug molecules. The trifluoromethyl group and the other functional groups present in the compound contribute to its potential as a key component in the formulation of innovative therapeutic agents.

InChI:InChI=1/C15H9ClF3NO3/c16-12-5-4-10(7-11(12)14(22)23)20-13(21)8-2-1-3-9(6-8)15(17,18)19/h1-7H,(H,20,21)(H,22,23)

Upstream product

• 89-54-3 2-chloro-5-aminobenzoic acid 
• 2251-65-2 3-(Trifluoromethyl)benzoyl chloride 

Downstream Products

• 937013-55-3 N-(4-chloro-3-hydroxymethyl-phenyl)-3-trifluoromethyl-benzamide 
• 942630-77-5 C₂₁H₁₇ClF₃N₃O₂S 
• 1001341-11-2 N-(2-amino-pyrimidin-5-yl)-2-chloro-5-(3-trifluoromethyl-benzoylamino)benzamide 
• 1001340-05-1 4-(4-{5-[2-chloro-5-(3-trifluoromethyl-benzoylamino)-benzoylamino]-pyrimidin-5-ylamino}-benzenesulfonyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1630970-11-4 C₃₀H₂₆ClF₃N₆O₄ 
• 937013-57-5 N-(4-chloro-3-formyl-phenyl)-3-trifluoromethyl-benzamide 
• 1179356-92-3 C₂₄H₁₆ClF₃N₆O 

Relevant academic research and scientific papers

2-AMINO-5-SUBSTITUTED PYRIMIDINE INHIBITORS

Compounds having the general structure (A) are provided. The compounds of the invention are capable of inhibiting kinases, such as members of the Src kinase family, Vegfr and various other specific receptor and non-receptor kinases. Formula (I):

CHEMICAL COMPOUNDS

The invention relates to chemical compounds, or pharmaceutically acceptable salts thereof of the formula which possess CSF 1R kinase inhibitory activity and are accordingly useful for their anti cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm blooded animal such as man.