896160-74-0

Basic information

• Product Name: Benzoic acid, 5-[[3-(1-cyano-1-methylethyl)benzoyl]amino]-2-methyl-, methyl ester
• CAS NO: 896160-74-0
• Molecular Formula: C20H20N2O3
• Molecular Weight: 336.39
• Mol File: 896160-74-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 5-[[3-(1-cyano-1-methylethyl)benzoyl]amino]-2-methyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 5-[[3-(1-cyano-1-methylethyl)benzoyl]amino]-2-methyl-, methyl ester(896160-74-0)
• EPA Substance Registry System: Benzoic acid, 5-[[3-(1-cyano-1-methylethyl)benzoyl]amino]-2-methyl-, methyl ester(896160-74-0)

Safety Data

• Hazardous Substances Data: 896160-74-0(Hazardous Substances Data)

Upstream product

• 872091-00-4 3-(1-cyano-1-methylethyl)benzoic acid 
• 18595-12-5 methyl 5-amino-2-methylbenzoate 

Downstream Products

• 896160-38-6 5-(3-(2-cyanopropan-2-yl)benzamido)-2-methylbenzoic acid 
• 1351237-97-2 5-(3-(2-cyanopropan-2-yl)benzamido)-2-methyl-N-(thieno[2,3-b]pyrazin-6-yl)benzamide 

Relevant articles and documents

Identification of amidoheteroaryls as potent inhibitors of mutant (V600E) B-Raf kinase with in vivo activity

A series of amidoheteroaryl compounds were designed and synthesized as inhibitors of B-Raf kinase. Several compounds from the series show excellent potency in biochemical, phenotypic and mode of action cellular assays. Potent examples from the series have also demonstrated good plasma exposure following an oral dose in rodents and activity against the Ras-Raf pathway in tumor bearing mice.