89617-55-0

Basic information

• Product Name: Acetamide, N-methyl-N-(1-methyl-2-phenylethyl)-, (S)-
• Synonyms: N-Methyl-N-((S)-1-methyl-2-phenyl-ethyl)-acetamide;N-acetyl desoxyephedrine
• CAS NO: 89617-55-0
• Molecular Formula: C12H17NO
• Molecular Weight: 191.273
• Mol File: 89617-55-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 87 - 88 °C (0.1 mmHg)
• CAS DataBase Reference: Acetamide, N-methyl-N-(1-methyl-2-phenylethyl)-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-methyl-N-(1-methyl-2-phenylethyl)-, (S)-(89617-55-0)
• EPA Substance Registry System: Acetamide, N-methyl-N-(1-methyl-2-phenylethyl)-, (S)-(89617-55-0)

Safety Data

• Hazardous Substances Data: 89617-55-0(Hazardous Substances Data)

Upstream product

• 2272-83-5 (1R,2S)-N-<(2-Hydroxy-2-phenyl)-1-methyl-ethyl>-N-methylacetamid 

Downstream Products

• 537-46-2 Methamphetamin 
• 4458-62-2 1-methyl-4-phenylazetidin-2-one 

Relevant articles and documents

A PROCESS FOR THE PREPARATION OF R-(-)-N, α-DIMETHYLPHENETHYLAMINE (LEVMETAMFETAMINE) OR S-(+)-N, α-DIMETHYLPHENETHYLAMINE (METHAMPHETAMINE) FROM d-EPHEDRINE OR L-EPHEDRINE RESPECTIVELY

A process for synthesis of R-(-)-N, α -Dimethylphenethylamine (Levmetamfetamine, formula I), or S-(+)-N, α - Dimethyl phenethylamine (Methamphetamine, formula II ), from d-ephedrine of formula III or l-ephedrine formula IV, the process comprising the steps of (a) acylating the d- or l-ephedrine base of formula III or formula IV with an acylating agent to make a reaction mixture containing a N- acylated ephedrines of formula V or formula VI ; (b) deoxygenation of N-acylated ephedrines to make the compound of the formula VII or Formula VIII by using Raney Nickel catalyst ; and (c) acid hydrolysis of the above deoxygenated products to get the levmetamfetamine or methamphetamine.