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α-D-xylothymine is a synthetic nucleoside analog, chemically known as 2'-deoxy-2'-fluoro-5-methyluridine. It is structurally similar to thymidine, a naturally occurring nucleoside in DNA, but with a fluorine atom replacing the hydroxyl group at the 2' position and a methyl group at the 5-position. This modification enhances its stability and resistance to degradation by enzymes, which can lead to improved pharmacokinetic properties. α-D-xylothymine has been studied for its potential antiviral activity, particularly against herpes simplex virus (HSV), due to its ability to inhibit viral DNA synthesis. The compound is of interest in the field of medicinal chemistry for the development of new antiviral drugs.

89618-08-6

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89618-08-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 89618-08-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,6,1 and 8 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 89618-08:
(7*8)+(6*9)+(5*6)+(4*1)+(3*8)+(2*0)+(1*8)=176
176 % 10 = 6
So 89618-08-6 is a valid CAS Registry Number.

89618-08-6Downstream Products

89618-08-6Relevant academic research and scientific papers

Systematic Synthesis and Biological Evaluation of α- and β-D-Xylofuranosyl Nucleosides of the Five Naturally Occurring Bases in Nucleic Acids and Related Analogues

Gosselin, Gilles,Bergogne, Marie-Chistine,Rudder, Jean de,Clercq, Erik De,Imbach, Jean-Louis

, p. 203 - 213 (2007/10/02)

The α- and β-D-xylofuranosyl analogues of the naturally occurring nucleosides, as well as other D-xylofuranosyl derivatives, have been the subject of a systematic synthesis and examination of their biological, i.e. antiviral antimetabolic, and cytostatic

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