89639-09-8Relevant academic research and scientific papers
Synthesis of a Novel Series of (Aryloxy)propanolamines: New Selective β2-Blocking Agents
Carre, Marie-Christiane,Youlassani, Alphonse,Caubere, Paul,Saint-Aubin-Floch, Anne,Blanc, Marie,Advenier, Charles
, p. 792 - 799 (2007/10/02)
A new family of β-blocking drugs is described.The originality of the new molecules lies in their functionalized hydrophobic folded structure, the basic part of which contains a benzocyclobutene ring.Excellent β2-blocker selectivity has been obtained with some of these compounds.Interestingly, this selectivity was not modified toward β1-blocker activity by introduction of the usual β1 inducer groups.
