89642-47-7

Upstream product

• 50803-23-1 4-bromo-3-(chlorosulfonyl)benzoic acid 
• 586-76-5 4-Bromobenzoic acid 

Downstream Products

• 1135370-65-8 2-bromo-5-(morpholine-4-carbonyl)benzenesulfonyl chloride 
• 1445796-54-2 C₁₈H₁₆BrF₃N₂O₄S 
• 1445791-13-8 C₂₀H₁₉F₃N₂O₆S 
• 1445795-92-5 C₁₉H₁₉F₃N₂O₅S 
• 1445796-53-1 C₁₃H₆BrClF₃NO₃S 

Relevant academic research and scientific papers

AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS

Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.

HEPATITIS B ANTIVIRAL AGENTS

The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention.

N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS

The invention relates to N-hydroxylsulfonamide derivatives for formula (I), (II) or (III), in which the variables are as defined in the claims, that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. N-hydroxylsulfonamide derivatives release HNO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of the functional groups on the N-hydroxylsulfonamide derivatives.