896459-20-4Relevant academic research and scientific papers
Synthesis, SAR, and atropisomerism of imidazolopyrimidine DPP4 inhibitors
O'Connor, Stephen P.,Wang, Ying,Simpkins, Ligaya M.,Brigance, Robert P.,Meng, Wei,Wang, Aiying,Kirby, Mark S.,Weigelt, Carolyn A.,Hamann, Lawrence G.
scheme or table, p. 6273 - 6276 (2010/11/18)
The synthesis and SAR of aminomethyl-substituted imidazolopyrimidine DPP4 inhibitors bearing varied pendant aryl groups is described. Compound 1, which exists as a separable mixture of non-interconvertible atropisomers was used as the starting point for i
