896459-26-0Relevant academic research and scientific papers
Synthesis and SAR of azolopyrimidines as potent and selective dipeptidyl peptidase-4 (DPP4) inhibitors for type 2 diabetes
Brigance, Robert P.,Meng, Wei,Fura, Aberra,Harrity, Thomas,Wang, Aiying,Zahler, Robert,Kirby, Mark S.,Hamann, Lawrence G.
scheme or table, p. 4395 - 4398 (2010/09/18)
Several pyrazolo-, triazolo-, and imidazolopyrimidines were synthesized and evaluated as inhibitors of DPP4. Of these three classes of compounds, the imidazolopyrimidines displayed the greatest potency and demonstrated excellent selectivity over the other
AZOLOPYRIMIDINE-BASED INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND METHODS
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Page/Page column 74-75, (2008/06/13)
Compounds are provided having the formula (I): Formula (I) wherein R, X, Y, A and n are as defined herein.
