896462-56-9Relevant academic research and scientific papers
Synthesis and biological evaluation of (3,4,5-trimethoxyphenyl)indol-3-ylmethane derivatives as potential antivascular agents
Dupeyre, Gregory,Chabot, Guy G.,Thoret, Sylviane,Cachet, Xavier,Seguin, Johanne,Guenard, Daniel,Tillequin, Francois,Scherman, Daniel,Koch, Michel,Michel, Sylvie
, p. 4410 - 4426 (2007/10/03)
Combretastatin A-4 (CSA-4), a stilbene derivative, is a potent vascular disrupting agent (VDA) with the structural requirement of a cis-configuration to maintain a molecular geometry and a correct orientation of both phenyl groups. A series of indolic ana
