896463-14-2

Upstream product

• 501-53-1 benzyl chloroformate 
• 896463-13-1 (3S,6R,7R,9aR)-6-Benzyloxycarbonylamino-7-hydroxymethyl-5-oxo-octahydro-pyrrolo[1,2-a]azepine-3-carboxylic acid tert-butyl ester 
• 851544-52-0 (3R,4R,7R,10S)-3-amino-1-aza-2-oxo-4-hydroxymethyl-bicyclo[5.3.0]decanecarboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

PEPTIDOMIMETIC COMPOUNDS AND PREPARATION OF BIOLOGICALLY ACTIVE DERIVATIVES

The invention relates to novel cyclic peptidomimetic compounds containing the sequence RGD for the preparation of appropriately functionalised antagonists of αvβ3 and αvβ5 integrins, and intended, for example, for the treatment of altered angiogenic pheno

Click chemistry to functionalise peptidomimetics

Sharpless modified Huisgen's [2+3] cycloaddition of azide and acetylenic derivatives was employed as an efficient and simple method to conjugate azabicycloalkane amino acids, mimics of a homoSer-Pro dipeptide, with biologically relevant partners.