896469-22-0Relevant articles and documents
Chiral cinchona alkaloid-thiourea catalyzed mannich reaction for enantioselective synthesis of β-amino ketones bearing benzothiazol moiety
Lin, Peng,Song, Baoan,Bhadury, Pinaki S.,Hu, Deyu,Zhang, Yuping,Jin, Linhong,Yang, Song
, p. 2433 - 2438 (2011)
Mannich reactions of imine with acetylacetone were effectively catalyzed by the modified chiral cinchona alkaloid-derived thiourea. The reactions led to chiral β-amino carbonyl compounds in high yields and good enantioselectivities. The study demonstrated
A compound with anti-virus activity of the benzothiazole heterocyclic chiral α - aminophosphonic acid ester compound and its preparation and use
-
Paragraph 0099; 0103; 0104, (2017/12/28)
The present invention discloses a class of chiral alpha-amino phosphonate ester compounds having anti-virus activity and containing benzothiazole heterocycle, preparation and applications thereof, wherein the structure of the compound is represented by th
Asymmetric synthesis and bioselective activities of α-amino-phosphonates based on the dufulin motif
Zhang, Guoping,Hao, Gefei,Pan, Jianke,Zhang, Jian,Hu, Deyu,Song, Baoan
, p. 4207 - 4213 (2016/06/14)
The asymmetric synthesis of enantiomerically pure α-aminophosphonates with high and bioselective activities is a challenge. Here, we report that both enantiomers of α-aminophosphonates bearing the N-benzothiazole moiety can be prepared in high yields (up
Enantioselective synthesis of β-amino esters bearing a benzothiazole moiety via a Mannich-type reaction catalyzed by a cinchona alkaloid derivative
Li, Liang,Song, Bao-An,Bhadury, Pinaki S.,Zhang, Yu-Ping,Hu, De-Yu,Yang, Song
supporting information; experimental part, p. 4743 - 4746 (2011/10/09)
Novel β-amino esters bearing a bioactive benzothiazole moiety were obtained with high enantioselectivities (up to 95 % ee) through a Mannich-type reaction of different imines with malonate in the presence of a new chiral cinchona alkaloid thiourea catalys