896473-02-2Relevant academic research and scientific papers
Synthesis of conformationally constrained diaminodicarboxylic acid derivatives
Weatherhead, Robin A.,Carducci, Michael D.,Mash, Eugene A.
experimental part, p. 8773 - 8778 (2010/03/02)
(Chemical Presented) Functionally protected forms of three conformationally constrained diaminodicarboxylic acids were synthesized and characterized. 2,2′-Diaminospiro[3.3]heptane-2,2′-dicarboxylic acid, an analogue of diaminopimelic acid, was prepared in
Synthesis and DNA binding studies of bis-intercalators with a novel spiro-cyclic linker
Chu, Yongjun,Lynch, Vincent,Iverson, Brent L.
, p. 5536 - 5548 (2007/10/03)
Threading polyintercalation has been demonstrated as a unique DNA binding mode in which a polyintercalating moiety threads back and forth through the DNA double helix. This binding topology necessitates linkers residing in both the minor and major grooves
