896473-07-7

Upstream product

• 1659-95-6 dimethyl 1,3-cyclohexadiene-1,4-dicarboxylate 

Downstream Products

• 1030841-05-4 1,4-bis(tert-butyl-dimethylsilanyloxymethyl)cyclohexa-1,3-diene 
• 896473-15-7 1,4-bis-(N-benzoyl(thiocarbamoyl)amino)-1,4-dimethoxycarbonyl-cyclohexane 
• 896473-10-2 (4-ethoxycarbonylamino-1,4-bis-methoxy-methoxymethyl-cyclohexyl)-carbamic acid ethyl ester 
• 896473-13-5 1,4-bis-tert-butoxycarbonylamino-cyclohexane-1,4-dicarboxylic acid dimethyl ester 
• 896473-12-4 1,4-bis-tert-butoxycarbonylamino-cyclohexane-1,4-dicarboxylic acid 
• 896473-11-3 (4-tert-butoxycarbonylamino-1,4-bis-hydroxymethyl-cyclohexyl)-carbamic acid tert-butyl ester 
• 896473-14-6 1,4-diamino-cyclohexane-1,4-dicarboxylic acid dimethyl ester 

Relevant academic research and scientific papers

Unexpectedly similar charge transfer rates through benzo-annulated bicyclo[2.2.2]octanes

A 4-(pyrrolidin-1-yl)phenyl electron donor and 10-cyanoanthracen-9-yl electron acceptor are attached via alkyne linkages to the bridgehead carbon atoms of bicyclo[2.2.2]octane and all three benzo-annulated bicyclo[2.2.2] octanes. The σ-system of bicyclo[2.2.2]octane provides a scaffold having nearly constant bridge geometry on which to append multiple, weakly interacting benzo π-bridges, so that the effect of incrementally increasing numbers of π-bridges on electron transfer rates can be studied. Surprisingly, photoinduced charge transfer rates measured by transient absorption spectroscopy in toluene show no benefit from increasing the number of bridge π-systems, suggesting dominant transport through the σ-system. Even more surprisingly, the significant changes in hybridization undergone by the σ-system as a result of benzo-annulation also appear to have no effect on the charge transfer rates. Natural Bond Orbital analysis is applied to both σ- and π-communication pathways. The transient absorption spectra obtained in 2-methyltetrahydrofuran (MTHF) show small differences between the benzo-annulated molecules that are attributed to changes in solvation. All charge transfer rates increase significantly upon cooling the MTHF solutions to their glassy state. This behavior is rationalized using combined molecular dynamics/electronic structure trajectories.

Synthesis and DNA binding studies of bis-intercalators with a novel spiro-cyclic linker

Threading polyintercalation has been demonstrated as a unique DNA binding mode in which a polyintercalating moiety threads back and forth through the DNA double helix. This binding topology necessitates linkers residing in both the minor and major grooves