89649-47-8Relevant academic research and scientific papers
On the Formation of N-Heterocycles by Thermolysis of Conjugated α-Azidoacrylates
Vogel, Claus,Delavier, Paul,Schnippenkoetter, Bernd
, p. 1591 - 1606 (2007/10/02)
The synthesis of various o-butadienyl-α-azidocinnamates 2 and β-cycloalkenyl-α-azidoacrylates 9 is described.The thermolysis of compounds 2 in solution yields the new 8,9-benzo-6-azabicyclonona-3,6,8-trienes 3 as major products, while that of 9 yields the cycloalkano-2H-pyrroles 10, which can rearrange to the cycloalkano-1H-pyrroles 11 at higher temperatures.A β-(o-vinyl)phenanthryl-α-azidoacrylate 12 was found to react on thermolysis both as a β-cycloalkenyl-α-azidoacrylate and a o-vinyl-α-azidocinnamate. - Keywords: α-Azidoacrylates, thermolysis of / α-Azidocinnamates, thermolysis of / 1H-Pyrroles / 2H-Pyrroles
The Synthesis and Chemistry of Azolenines. Part 2. A General Synthesis of Pyrrole-2-carboxylic Acid Derivatives by the Reaction of 2H-Azirines with Enamines, and the Crystal and Molecular Structure of Ethyl 3-Phenyl-4,5,6,7-tetrahydroindole-2-carboxylate
Law, Kam Wah,Lai, Ting-Fong,Sammes, Michael P.,Katritzky, Alan R.,Mak, Thomas C.W.
, p. 111 - 118 (2007/10/02)
A new general synthesis of 1H-pyrrole-2-carboxylic acid derivatives is described.Reaction between appropriately substituted 2H-azirines and enamines gives a mixture of 2,3- and 3,4-dihydropyrroles, which on acid treatment yields the title compounds in mod
