896507-37-2Relevant articles and documents
Oligoresorcinols fold into double helices in water
Goto, Hidetoshi,Katagiri, Hiroshi,Furusho, Yoshio,Yashima, Eiji
, p. 7176 - 7178 (2006)
We report the first double helices with a controlled helicity in water based on oligoresorcinols as a new, simplest water-soluble structural motif. The molecular strands of the oligoresorcinols self-assemble into double helices with the aid of aromatic interactions in water as characterized by 1H NMR and absorption spectroscopies together with the X-ray crystallographic study of the pentamer. The double helix formation is sensitive to the chain length, solvent composition, and temperature. Moreover, a bias in the screw sense of the double helices was achieved by covalently attaching chiral substituents to both ends of the molecular strands. Copyright