89652-23-3Relevant academic research and scientific papers
Cerium ammonium nitrate-catalyzed aerobic oxidative coupling of dithiocarbamates: Facile synthesis of thioureas and bis(aminothiocarbonyl)disulfides
Li, Tian-Tian,Song, Xiang-Hai,Wang, Mei-Shuang,Ma, Ning
, p. 40054 - 40060 (2014/12/10)
Diverse disubstituted and trisubstituted thioureas were synthesized by the condensation of dithiocarbamate TEA (or DABCO) salts and amines using cerium ammonium nitrate (CAN) as a catalyst in high yields at room temperature. It is a one-pot method and it is unnecessary to isolate isothiocyanates. This reaction probably took place through nucleophilic addition of amines to isothiocyanates, which were generated by oxidative coupling of dithiocarbamates and the following decomposition of bis(aminothiocarbonyl)disulfides. When secondary amines and CS2served as the reactants, bis(aminothiocarbonyl)disulfides were obtained via tandem nucleophilic addition/oxidative coupling reactions in moderate to excellent yields. In all the coupling reactions, the oxidant was air and CAN possibly acted as an SET catalyst.
Three-component reaction between isocyanides, aliphatic amines and elemental sulfur: Preparation of thioureas under mild conditions with complete atom economy
Nguyen, Thanh Binh,Ermolenko, Ludmila,Al-Mourabit, Ali
, p. 3172 - 3179 (2015/01/09)
The reaction of isocyanides with aliphatic amines in the presence of elemental sulfur was found to proceed efficiently at, or near, room temperature to produce thioureas in excellent yields and with complete atom economy.
Heterocycle formation via palladium-catalyzed intramolecular oxidative C-H bond functionalization: An efficient strategy for the synthesis of 2-aminobenzothiazoles
Joyce, Laurie L.,Batey, Robert A.
supporting information; experimental part, p. 2792 - 2795 (2009/11/30)
N-Arylthioureas are converted to 2-aminobenzothiazoles via Intramolecular C-S bond formation/C-H functionalization utilizing an unusual cocatalytic Pd(PPh3)4MnO2 system under an oxygen atmosphere at 80 °C. This method elim
NEW FLUOROUS TAGGING AND SCAVENGING REACTANTS AND METHODS OF SYNTHESIS AND USE THEREOF
-
Page 58, 59, 61, 62, (2008/06/13)
The present invention includes methods and compositions for increasing the fluorous nature of an organic compound by reacting it with at least one fluorous compound to produce a fluorous tagged organic compound. The increased fluorous nature of the fluorous tagged organic compound can then be utilized to separate the fluorous organic compound from untagged reagents, reactants, catalysts and/or products derived therefrom. The resultant fluorous tagged organic compound can be subjected to subsequent chemical transformations, wherein the fluorous nature of the tagged compound is utilized to increase the ease of separation of the fluorous tagged organic compound from untagged reagents, reactants, catalysts and/or products derived therefrom, after each chemical transformation. The chemical transformations result in a second fluorous tagged organic compound wherein the fluorous nature of the second fluorous tagged organic compound can then be reduced by removing the fluorous group therefrom, thereby producing a second organic compound that may be employed as a pharmaceutical compound or intermediate, or a combinatorial library component.
Fluorous electrophilic scavengers for solution-phase parallel synthesis
Zhang, Wei,Chen, Christine Hiu-Tung,Nagashima, Tadamichi
, p. 2065 - 2068 (2007/10/03)
A fluorous isatoic anhydride and isocyanate are synthesized and used as scavengers for amines in solution-phase parallel synthesis of urea, thiourea, and β-hydroxyamine analogs. The resulting fluorous derivatives are readily separated from the reaction mi
Development of Thiourea-Based Ligands for the Palladium-Catalyzed Bis(methoxycarbonylation) of Terminal Olefins
Dai, Mingji,Wang, Cuihua,Dong, Guangbin,Xiang, Jing,Luo, Tuoping,Liang, Bo,Chen, Jiahua,Yang, Zhen
, p. 4346 - 4348 (2007/10/03)
Thiourea-based ligands were evaluated for the palladium-catalyzed bis(methoxycarbonylation) of terminal olefins. The usefulness of these ligands for this reaction is demonstrated by their stability to oxidizing agents, and their superiority in preventing
ω-Dialkylaminoalkyl esters of N-phenyl aminethiocarboximidic acids with local anesthetic and other activities
Ranise,Bondavalli,Bruno,Schenone,D'Amico,Parrillo,Marrazzo,Rossi
, p. 1263 - 1283 (2007/10/02)
A series of ω-dialkylaminoalkyl esters of N-phenyl aminethiocarboximidic acids was prepared by reaction of N-phenyl 1-pyrrolidine, 1-piperidine, 4-morpholine, 1,2,3,4-tetrahydro-1-quinoline, 1,2,3,4-tetrahydro-2-isoquinoline, 10-phenothiazine, N-phenyl-2-
