89665-36-1

Upstream product

• 20537-97-7 methylfumaroyl chloride 
• 71-43-2 benzene 
• 89665-35-0 2-methylene-1,4-diphenylbutane-1,4-dione 
• 89680-36-4 N-(trimethylsilylmethyl)pyridinium triflate 
• 959-28-4 1,4-diphenylbut-2-ene-1,4-dione 
• 591-50-4 iodobenzene 
• 104516-09-8 1-phenylbuta-2,3-dien-1-ol 
• 201230-82-2 carbon monoxide 

Downstream Products

• 88073-35-2 (Z)-2-methyl-1,4-diphenylbut-2-ene-1,4-dione 
• 84302-11-4 3-methyl-2,5-diphenylfuran 
• 54980-33-5 phenyl 5-phenyl-3-furyl ketone 
• 412300-17-5 3-bromo-4-methyl-2,5-diphenyl-furan 
• 101576-06-1 3-dibromomethyl-2,5-diphenyl-furan 
• 500346-25-8 3-bromo-4-bromomethyl-2,5-bis-(4-bromo-phenyl)-furan 
• 412277-65-7 3-bromo-2,5-bis-(4-bromo-phenyl)-4-methyl-furan 
• 412300-58-4 acetic acid-(4-methyl-2,5-diphenyl-[3]furyl ester) 
• 873420-84-9 2-chloro-4-methyl-2,5-diphenyl-furan-3-one 
• 101446-25-7 2-bromo-3-methyl-1,4-diphenyl-but-2c-ene-1,4-dione 
• 101446-57-5 2-chloro-3-methyl-1,4-diphenyl-but-2c-ene-1,4-dione 
• 101576-05-0 3-bromo-4-bromomethyl-2,5-diphenyl-furan 
• 101576-47-0 3-chloro-4-chloromethyl-2,5-diphenyl-furan 
• 101602-20-4 (RS,SR)-2,3-dibromo-2-methyl-1,4-diphenyl-butane-1,4-dione 

Relevant academic research and scientific papers

Synthetic method for 2-butene-1,4-diketone compound

The invention discloses a synthetic method for a 2-butene-1,4-diketone compound, and belongs to the technical field of organic synthesis. According to the key point of the technical scheme of the synthetic method, the reaction equation in the synthesis pr

Tunable Synthesis of 2-Ene-1,4-diones, 4-Hydroxycyclopent-2-en-1-ones, and 2-(Furan-3-yl)acetamides via Palladium-Catalyzed Cascade Reactions of Allenols

An efficient and regioselective synthesis of 2-ene-1,4-diones, 4-hydroxycyclopent-2-en-1-ones, or 2-(furan-3-yl)acetamides is successfully realized through palladium-catalyzed one-pot multicomponent reactions of allenols with aryl iodides and carbon monoxide in the presence of tertiary amines. Interestingly, the selectivity depends on the substitution patterns of the allenol substrates. To be specific, from the reaction of allenols with no substituent attached on the internal position of the allenic moiety, 2-ene-1,4-diones or 4-hydroxycyclopent-2-en-1-ones were formed selectively through carbonylation of aryl iodide followed by acylation of allenol with the in situ formed acyl palladium species, β-hydride elimination of the in situ formed allyl palladium complex, and further tautomerization or intramolecular aldol reaction. From the reaction of allenols bearing a substituent at the internal position of the allenic unit, on the other hand, diversely substituted 2-(furan-3-yl)acetamides were formed through a cascade process combining carbonylation of aryl iodide, acylation, and carbonylation of allenol followed by intramolecular condensation and amination by tertiary amine featuring an oxidant-free C-N bond cleavage.

NEW C-C BOND FORMATION WITH PYRIDINIUM METHYLIDE: HYDROMETHYLENATION OF OLEFIN

New C-C bond formation with pyridinium methylide is presented: Pyridinium methylide reacts with electron-deficient olefins providing the next higher homologs of olefins, in which the double bond of starting olefin is saturated and, instead, a C=C double bond is newly formed.This reaction mode has been never reported before in the study of nitrogen ylide and is to be referred to as hydromethylenation of olefin.In the presence of base, 1,2-double bond migration occurs leading to the methylated derivatives of starting olefins.