89671-76-1Relevant academic research and scientific papers
Palladium-catalyzed tandem oxidative annulation of α-amino ketones leading to 2-aroylindoles
Jiang, Tao-Shan,Dai, Long,Zhou, Yuhui,Zhang, Xiuli
, (2020/01/08)
A simple synthesis of 2-aroylindoles via palladium-catalyzed tandem oxidative annulation directly from α-amino ketones has been developed. In this transformation, two-step reaction including oxidation of α-amino aetones to generate imine intermediates and
N-(2-Aminobenzylidene)-4-methylanilines - stable and cheap alternate for 2-aminobenzaldehydes: concise synthesis of 3-unsubstituted-2-aroylindoles
Vivekanand, Thavaraj,Sandhya, Thiruvalluvan,Vinoth, Perumal,Nagarajan, Subbiah,Maheswari, C. Uma,Sridharan, Vellaisamy
supporting information, p. 5291 - 5294 (2015/08/26)
Abstract Synthesis of 3-unsubstituted-2-aroylindoles starting from readily available N-(2-aminobenzylidene)-4-methylanilines, cheap and stable alternative to 2-aminobenzaldehydes, and α-bromoketones was achieved in moderate to good yields under basic cond
Synthesis of indoles through highly efficient cascade reactions of sulfur ylides and N-(ortho-chloromethyl)aryl amides
Yang, Qing-Qing,Xiao, Cong,Lu, Liang-Qiu,An, Jing,Tan, Fen,Li, Bin-Jie,Xiao, Wen-Jing
, p. 9137 - 9140 (2012/10/29)
Batting the ylides: A simple procedure carried out under mild conditions allows the direct and efficient synthesis of structurally diverse indoles. This approach involves a cascade reaction of sulfur ylides and N-(ortho-chloromethyl) aryl amides (see scheme). Copyright
SYNTHESIS OF 2-ACYLINDOLES FROM α-(N-ISATINYL) KETONES
Gorgos, V. I.,Zorin, L. M.,Zhungietu, G. I.,Rekhter, M. A.
, p. 1179 - 1181 (2007/10/02)
2-Acylindoles were synthesized by the recyclization of N-phenacyl- and N-acetonylisatins in alkaline medium and the decarboxylation of 2-acylindolyl-3-carboxylic acids or their salts in basic or neutral media.
