896718-27-7Relevant academic research and scientific papers
A convenient synthesis of medium-sized lactams through RCM reaction of oxyoxazolidinones
Kamimura, Akio,Tanaka, Keiichi,Hayashi, Takahiro,Omata, Yoji
, p. 3625 - 3627 (2007/10/03)
Oxyoxazolidinones, which are prepared from secondary O-acylmandelamides by treatment with TBSOTf, underwent the RCM reaction in the presence of Grubbs catalyst to give oxazoloazepines or oxazoloazecines, which were readily converted into N-unsubstituted seven-membered or eight-membered lactams by the reductive treatment.
