89676-62-0 Usage
Imidazole derivative
A compound based on the imidazole structure, which is a five-membered ring containing 3 carbon atoms and 2 nitrogen atoms.
Amino group
A functional group (-NH2) present in the compound, which contributes to its chemical reactivity and potential applications in pharmaceutical research.
Fluorine substituent
The presence of a fluorine atom (-F) in the compound, which can influence its chemical properties, stability, and biological activity.
Pharmaceutical research and drug development potential
The compound's unique structure and properties make it a promising candidate for use in the development of new pharmaceutical drugs and as a building block for synthesizing compounds with biological activity.
Building block for synthesizing new compounds
Due to its structure, 1H-Imidazole-4-carboxamide,2-amino-5-fluoro-(9CI) can be used as a starting point for creating new compounds with potential biological activity.
Starting material for pharmaceutical drug production
The compound can be used as a precursor in the synthesis of pharmaceutical drugs, potentially leading to the development of new medications.
Need for further research
To fully understand the potential uses and benefits of 1H-Imidazole-4-carboxamide,2-amino-5-fluoro-(9CI), additional research is required to explore its properties, applications, and possible therapeutic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 89676-62-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,6,7 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 89676-62:
(7*8)+(6*9)+(5*6)+(4*7)+(3*6)+(2*6)+(1*2)=200
200 % 10 = 0
So 89676-62-0 is a valid CAS Registry Number.
89676-62-0Relevant academic research and scientific papers
Photochemistry of Diazonium Salts. 5. Syntheses of 2,4-Difluoroimidazole-5-carboxylic Acid and Related Compounds
Takahashi, Kazuyuki,Kirk, Kenneth L.,Cohen, Louis A.
, p. 1951 - 1954 (2007/10/02)
Catalytic hydrogenolysis, effective for the synthesis of 2-aminoimidazoles from 2-(arylazo)imidazoles, cannot be used to prepare 2-amino-4-fluoroimidazoles because the fluorine atom is lost simultaneously; formamidinesulfinic acid, however, achieves the required conversion in good yield.Ethyl 2,4-difluoroimidazole-5-carboxylate is obtained by photolysis of ethyl 2-diazonio-4-fluoroimidazole-5-carboxylate in fluoroboric acid.The ester is saponified to the acid in 1 N base (without loss of fluorine) but is stable in 0.05 N base; the ester also resists ammonolysis to the carboxamide or hydride reduction to the carbinol.Ammonolysis of ethyl 2-amino-4-fluoroimidazole-5-carboxylate is successful, however, and the resulting carboxamide is converted, via diazotation and photolysis, into 2,4-difluoroimidazole-5-carboxamide.N-Alkyl derivatives of the difluoro ester undergo facile hydride reduction of the ester function, but only with prior reductive loss of fluorine at C-2.The difluoro acid is stable to diborane reduction over 1 month.These examples of resistance to normal carboxyl modification are ascribed to the facile generation of the imidazolate ion in basic media and a resulting large increase in electron density at the carbonyl carbon by resonance overlap.
