89677-75-8

Upstream product

• 861602-59-7 2-iodo-4-nitrobenzoyl chloride 
• 89459-38-1 4-nitro-2-iodobenzoic acid 
• 619-17-0 4-Nitroanthranilic acid 
• 7745-92-8 2-iodo-1-methyl-4-nitrobenzene 

Downstream Products

• 2835-68-9 4-aminobenzamide 
• 300627-43-4 2-iodo-4-nitrobenzonitrile 
• 300627-48-9 4-amino-2-iodobenzonitrile 
• 824936-26-7 (2R)-N-(4'-cyano-3'-iodophenyl)-3-bromo-2-hydroxy-2-methylpropanamide 
• 300627-64-9 4-[4,4-dimethyl-3-(4-hydroxybutyl)-5-imino-2-thioxo-1-imidazoldinyl]-2-iodobenzonitrile 
• 300627-68-3 DTIB 
• 300627-53-6 2-iodo-4-isothiocyanatobenzonitrile 

Relevant academic research and scientific papers

Synthesis of novel iodo derived bicalutamide analogs

A series of optically active nonsteroidal selective androgen receptor modulators with structures analogous to bicalutamide was prepared by replacing the trifluoromethyl group with iodine and the sulfonyl linker by oxygen.

Design, synthesis, and pharmacological characterization of 4-[4,4-Dimethyl-3-(4-hydroxybutyl)-5-oxo-2-thioxo-1-imidazolidinyl]-2-iodoben zonitrile as a high-affinity nonsteroidal androgen receptor ligand

4-[4,4-Dimethyl-3-(4-hydroxybutyl)-5-oxo-2-thioxo-1-imidazolidinyl]-2-trifluo romethylbenzonitrile (RU 59063) is a prototype of a new class of high-affinity nonsteroidal androgen receptor (AR) ligands. The search for a radioiodinated AR ligand prompted us