896854-73-2

Basic information

• Product Name: C₁₉H₂₂N₂O₃S
• CAS NO: 896854-73-2
• Molecular Weight: 358.461
• Mol File: 896854-73-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₂₂N₂O₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₂₂N₂O₃S(896854-73-2)
• EPA Substance Registry System: C₁₉H₂₂N₂O₃S(896854-73-2)

Safety Data

• Hazardous Substances Data: 896854-73-2(Hazardous Substances Data)

Upstream product

• 43009-18-3 4-methoxyphenyl dithiocarbamic acid triethylammonium 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 104-94-9 4-methoxy-aniline 
• 1745-07-9 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 2284-20-0 4-Methoxyphenyl isothiocyanate 

Relevant articles and documents

Synthesis and biological evaluation of dihydroisoquinoline-2(1H)- carbothioamide derivatives as TRPV1 antagonists

TRPV1 receptor is an important analgesia target. Its antagonists are expected to prevent pain perception by blocking the receptor directly. In this letter, eight dihydroisoquinoline-2(1H)-carbothioamide derivatives were designed and synthesized as TRPV1 antagonists. The benzene ring was modified with different substitutional groups. Preliminary biological tests suggested that the new compounds exhibited TRPV1 antagonist activity and different analgesia effects, some of which were promising as analgesia drugs.