897-56-3

Usage

Chemical structure

A derivative of naphthalene with a dimethylamino group and a phenylmethylene group attached to the amino group.

Properties

Fluorescent labeling reagent, high fluorescence quantum yield, reacts with primary and secondary amines to form stable, fluorescent derivatives.

Uses

Commonly used in biochemistry and molecular biology for the labeling of proteins, peptides, and nucleic acids for detection and imaging purposes. Also used in fluorescence microscopy, flow cytometry, and other analytical techniques, as well as for studying biological processes and interactions.

Upstream product

• 134-32-7 1-amino-naphthalene 
• 100-10-7 4-dimethylamino-benzaldehyde 

Relevant academic research and scientific papers

Analgesic, anti-inflammatory activity and docking study of 2-(substituted phenyl)-3-(naphthalen-1-yl)thiazolidin-4-ones

A potential analgesic and anti-inflammatory activities have been reported in 4-thiazolidinone analogs as well as some drugs bearing naphthyl moiety such as naproxen. Thus a reported series of 2-(substituted phenyl)-3-(naphthalen-1-yl)thiazolidin-4-ones (T

Analgesic, anti-inflammatory activity and docking study of 2-(substituted phenyl)-3-(naphthalen- 1-yl)thiazolidin-4-ones

A potential analgesic and anti-inflammatory activities have been reported in 4-thiazolidinone analogs as well as some drugs bearing naphthyl moiety such as naproxen. Thus a reported series of 2-(substituted phenyl)-3-(naphthalen-1-yl)thiazolidin-4- ones (

Synthesis and antimicrobial evaluation of some 4-thiazolidinone derivatives containing polynuclear hydrocarbon

Some 4-thiazolidinone derivatives have also been known to be associated with several biological activities thus can be utilized as promising scaffold for developing analogues. Aryl aldehydes were treated with naphthylamine to yield corresponding Schiff's

Synthesis and antibacterial activities of some schiff bases

Schiff bases p-hydroxybenzylidene-2-carboxyaniline, p-nitrobenzylidene-2- carboxyaniline, p-(N, N-dimethyl)aminobenzylidene-2-carboxyaniline, N-(4-hydroxybezylidene)-benzene-1,2-diamine, N-(4-nitrobezylidene)benzene-1,2- diamine,N-(4-(N, N-dimethylaminobezylidene)benzene-1,2-diamine, N-(4-(N,Ndimethylamino) benzylidene)naphthalen-1-amine,N-(4-nitrobenzylidene) naphthalen-1-amine,N-(4-chlorobenzylidene)naphthalen-1-amine,sodium-4-(4-(N, N-dimethyl amino)benzylideneamino)naphthalene-1-sulfonate,sodium -4-(4-nitrobenzylideneamino) naphthalene-1-sulfonate and sodium-4-(4- chlorobenzylideneamino) naphthalene-1-sulfonate obtained by condensation of aniline and naphthylamine derivatives with some aromatic aldehydes were characterized by physical and spectral methods. The biological activity of these products were as antibacterial agents against three species of human pathogenic bacteria such as Escherichia coli, Staphylococcus aureus and Klebsiella sp. Nearly 50% of these compounds showed reasonable activity against the bacterial species investigated and we found that the antibacterial activity is dependent on the molecular structure of the compounds.

A study of anti-inflammatory activity of some novel α-amino naphthalene and β-amino naphthalene derivatives

In the present study, some naphthalene derivatives have been synthesized by incorporating azetidinyl and thiazolidinyl moieties at its α- or β-positions such as a-(3-chloro-2-oxo-4-substitute-d)aryl-1-azetidinyl) naphthalenes 6-10, α-((substituted)aryl-4-