897014-78-7

Upstream product

• 897014-69-6 Acetic acid (2S,4R)-5-hydroxy-5-(4-methoxy-5-methylene-2-oxo-2,5-dihydro-furan-3-yl)-2,4-dimethyl-pentyl ester 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 90270-02-3 (2R,4S)-1-hydroxy-2,4-dimethylpentyl acetate 
• 168134-57-4 (2R,4S)-5-acetoxy-2,4-dimethyl-pentanal 

Downstream Products

• 897014-72-1 3-[(6E,8E,10E)-(2R,4S)-5-Hydroxy-1-(4-methoxy-benzyloxy)-2,4-dimethyl-dodeca-6,8,10-trienyl]-4-methoxy-5-methylene-5H-furan-2-one 
• 897014-84-5 4-Methoxy-3-[(6E,8E,10E)-(2R,4S)-1-(4-methoxy-benzyloxy)-2,4-dimethyl-5-oxo-dodeca-6,8,10-trienyl]-5-methylene-5H-furan-2-one 
• 897014-81-2 (2S,4R)-5-(4-Methoxy-benzyloxy)-5-(4-methoxy-5-methylene-2-oxo-2,5-dihydro-furan-3-yl)-2,4-dimethyl-pentanal 
• 897014-71-0 3-[(2R,4S)-5-Hydroxy-1-(4-methoxy-benzyloxy)-2,4-dimethyl-pentyl]-4-methoxy-5-methylene-5H-furan-2-one 

Relevant academic research and scientific papers

Formal synthesis of Abyssomicin C

An alternative strategy towards Abyssomicin C (1) is described. The key ene-diene intermediate is synthesized via a Kishi type coupling of an E/Z mixture of triene-iodide 7 and a suitably functionalized derivative of 2,4-dimethylglutaric acid. A final in