897016-91-0

Upstream product

• 105-58-8 Diethyl carbonate 
• 3430-13-5 5-bromo-2-methylpyridine 
• 98-80-6 phenylboronic acid 
• 3256-88-0 5-phenyl-2-picoline 

Downstream Products

• 1639441-23-8 C₂₇H₂₉NO₆ 
• 1639441-47-6 C₁₉H₁₉NO₂ 
• 1639441-32-9 C₂₁H₂₃NO₅ 

Relevant academic research and scientific papers

OXADIAZOLE DERIVATIVE HAVING ENDOTHELIAL LIPASE INHIBITORY ACTIVITY

Disclosed is a compound which is useful as an endothelial lipase inhibitor. A compound represented by the formula: its pharmaceutically acceptable salt, or a solvate thereof, wherein Ring A is aromatic carbocycle or aromatic heterocycle,Z is —NR5—, —O— or —S—,R5 is hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted aryl or the like,R1 is hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl or the like,R2 and R3 are each independently hydrogen, halogen, hydroxy or the like,R4 is a group represented by the formula: —(CR6R7)n-R8, wherein R6 and R7 are each independently hydrogen, halogen, hydroxy or the like, n is an integer of 0 to 3, R8 is carboxy, cyano, substituted or unsubstituted alkyl or the like, Rx is halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl or the like,m is an integer of 0 to 3.

Compositions and methods of treating cell proliferation disorders

The invention relates to compounds and methods for treating cell proliferation disorders.