897017-87-7

Upstream product

• 269410-22-2 4-hydroxy-3-methoxyphenylboronic acid pinacol ester 
• 867313-37-9 methyl 1-(4-hydroxy-3-methoxyphenyl)-8-isopropoxy-9-methoxy-5,6-dihydropyrrolo[2,1-a]isoquinoline-3-carboxylate 
• 867313-39-1 methyl 2-bromo-8-isopropoxy-1-(4-isopropoxy-3-methoxyphenyl)-9-methoxy-5,6-dihydropyrrolo[2,1-a]isoquinoline-3-carboxylate 
• 867313-38-0 methyl 8-isopropoxy-1-(4-isopropoxy-3-methoxyphenyl)-9-methoxy-5,6-dihydropyrrolo[2,1-a]isoquinoline-3-carboxylate 
• 850346-74-6 methyl 1-bromo-8-isopropoxy-9-methoxy-5,6-dihydropyrrolo[2,1-a]isoquinoline-3-carboxylate 
• 850346-72-4 methyl 8-isopropoxy-9-methoxy-5,6-dihydropyrrolo[2,1-a]isoquinoline-3-carboxylate 
• 850346-70-2 methyl 1-[2-bromo-5-isopropoxy-4-methoxyphenethyl]-1H-pyrrole-2-carboxylate 
• 897017-84-4 methyl 2-(4-hydroxyphenyl)-8-isopropoxy-1-(4-isopropoxy-3-methoxyphenyl)-9-methoxy-5,6-dihydropyrrolo[2,1-a]isoquinoline-3-carboxylate 

Relevant academic research and scientific papers

Synthesis and structure-activity relationship study of potent cytotoxic analogues of the marine alkaloid lamellarin D

The marine alkaloid, Lamellarin D (Lam-D), has shown potent cytotoxicity in numerous cancer cell lines and was recently identified as a potent topoisomerase I inhibitor. A library of open lactone analogues of Lam-D was prepared from a methyl 5,6-dihydropy