89706-87-6Relevant academic research and scientific papers
Cyclic amidino agents useful as nitric oxide synthase inhibitors
-
, (2008/06/13)
The current invention discloses useful amidino derivative useful as nitric oxide synthase inhibitors.
Azepine derivatives useful as nitric oxide synthase inhibitors
-
, (2008/06/13)
The current invention discloses azepine derivatives useful as nitric oxide synthase inhibitors.
2-Iminopyrrolidines as potent and selective inhibitors of human inducible nitric oxide synthase
Hagen, Timothy J.,Bergmanis, Arija A.,Kramer, Steven W.,Fok, Kam F.,Schmelzer, Albert E.,Pitzele, Barnett S.,Swenton, Lydia,Jerome, Gina M.,Kornmeier, Christine M.,Moore, William M.,Branson, Linda F.,Connor, Jane R.,Manning, Pamela T.,Currie, Mark G.,Hallinan, E. Ann
, p. 3675 - 3683 (2007/10/03)
A series of substituted 2-iminopyrrolidines has been prepared and shown to be potent and selective inhibitors of the human inducible nitric oxide synthase (hiNOS) isoform versus the human endothelial nitric oxide synthase (heNOS) and the human neuronal ni
New Synthetic Methods. Conjugate Addition of Alkyl Groups to Electron Deficient Olefins with Nitroalkanes as Alkyl Anion Equivalents
Ono, Noboru,Kamimura, Akio,Miyake, Hideyoshi,Hamamoto, Isami,Kaji, Aritsune
, p. 3692 - 3698 (2007/10/02)
The sequence of the Michael addition of nitroalkanes and denitration from the adduct provides a new and general method for conjugate addition of primary and secondary alkyl groups to electron deficient olefins such as α,β-unsaturated aldehydes, ketones, esters, nitriles, sulfoxides, and sulfones.
