89708-58-7

Upstream product

• 90878-79-8 5,5-(ethylenedioxy)-4aβ-methylperhydronaphthalen-1-one 
• 85532-87-2 C₁₄H₂₂O₃ 
• 85532-84-9 C₁₄H₂₀O₄ 
• 85532-85-0 C₁₅H₂₄O₄ 
• 54100-20-8 5-methoxy-8a-methyl-3,4,8,8a-tetrahydro-2H,7H-naphthalene-1,6-dione 
• 13307-75-0 (phenylthio)methyllithium 
• 89656-01-9 (4aS,6S,8aS)-2-[1-Butylsulfanyl-meth-(E)-ylidene]-6,8a-dimethyl-5-methylene-octahydro-naphthalen-1-one 
• 100432-12-0 5,5-(ethylenedioxy)-2,4a-dimethylperhydronaphthalen-1-ol 
• 100432-18-6 C₂₁H₂₄O₅ 
• 100432-20-0 C₁₈H₂₆O₆ 
• 100432-19-7 C₁₇H₂₄O₆ 
• 100432-14-2 5,5-(ethylenedioxy)-2,2-(ethylenedithio)-4aβ-methyl-2,3,4,4a,5,6,7,8-octahydronaphthalene 
• 70499-16-0 4a′-methyl-4′,4a′,7′,8′-tetrahydro-3′H-spiro[[1,3]dithiolane-2,2′-naphthalen]-5′(6′H)-one 
• 100432-21-1 2-(hydroxymethylene)-6β,8aβ-dimethyl-5-methylene-trans-perhydronaphthalen-1-one 

Downstream Products

• 60114-23-0 (+/-)-colorata-4(13)8-dienolide 

Relevant academic research and scientific papers

A Stereoselective Total Synthesis of (+/-)-Muzigadial

A stereoselective 14-step, total synthesis of (+/-)-muzigadial (1a, 11percent overall yield), starting from the commercially available Wieland-Miescher ketone (5), via intermediate ketone 13, is described.The two additional chiral centers in 13 were incorporated by equilibrium of the mixture of stereoisomeric ketones 10 to the most favorable isomer, 10a.The key step for introducing the necessary functionality at C-1 involved the regio- and stereoselective cis hydroxylation of enol ether 37b with osmium tetraoxide in the presence of tert-butyl hydroperoxide.

THE TOTAL SYNTHESIS OF (+/-)-COLORATA-4(13),8-DIENOLIDE

The total synthesis of (+/-)-colorata-4(13),8-dienolide (1), a sesquiterpene with a rearranged drimane skeleton, is described using 6β, 8aβ-dimethyl-5-methylene-3,4,4aα,5,6,7,8,8a-octahydro-1(2H)-naphtalenone (10) as a key intermediate.A new annelation me