897364-32-8

Upstream product

• 371-41-5 4-Fluorophenol 
• 206193-17-1 (2R)-3-bromo-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide 
• 654-70-6 4-amino-2-trifluoromethylbenzonitrile 
• 1019972-88-3 (R)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 541497-95-4 (2S)-N-(4-cyano-3-trifluoromethylphenyl)-3-(4-fluorophenoxy)-2-hydroxy-2-methylpropionamide 

Relevant academic research and scientific papers

Cesium fluoride and tetra-n-butylammonium fluoride mediated 1,4-N→O shift of disubstituted phenyl ring of a bicalutamide derivative

A novel 1,4-N→O migration of a disubstituted phenyl ring was observed during N-methylation of a bicalutamide derivative, (2S)-2-(tert-butyldimethylsilanyloxy)-N-(4-cyano-3-trifluoromethylphenyl)-3-(4-fluorophenoxy)-2-methylpropionamide, in the presence of